Zoloft Side Effects

Zoloft (sertraline) is an antidepressant drug that increases the availability of some chemicals in the brain and it is used in the treatment of depression, obsessive compulsive disorders, panic disorders and anxiety.

You should contact your doctor immediately if you develop signs of any allergic reaction to Zoloft such as difficulty in breathing, hives or skin rash, face swelling, swelling in the tongue, throat and lips. Inform your doctor about symptoms associated with behavioral changes, mood swings, panic disorders and insomnia. Call your doctor at once if you have:

Inform your doctor if you have any of the following to make ensure safety while you use Zoloft:

  • Suicidal ideations or past records of drug abuse
  • Un-resolving blood clotting disorder
  • Kidney or liver damage
  • Convulsion, seizure or epilepsy
  • Manic depression

Common Zoloft side effects may include:

  • Restlessness, dizziness and drowsiness
  • Constipation and Stomach upset
  • Dry mouth
  • Weight loss or anorexia
  • Insomnia (sleep problems)
  • Decreased libido or difficulty in reaching orgasm

The above list of side effects of Zoloft is not exhaustive. Consult your doctor for medical advice about Zoloft sexual side effects in men and how it can be managed. Zoloft side effects first week of visits must be ensured to check patients’ progress.

The common side effects of Zoloft include nausea, loose stools, dizziness, tremor, dyspepsia, fatigue, paresthesia, headache, anxiety, anorexia, malaise, pain, delayed ejaculation, decreased libido, vomiting, constipation, stomach upset, agitation, and hypouricemia.

If you experience any of the following side effects while taking sertraline, consult with your doctor immediately:

More common Zoloft side effects

  • Lowered sexual drive or ability
  • Delayed or failed ejaculation

Less common or rare Zoloft side effects

  • Nosebleeds
  • Shivering
  • Diarrhea
  • Aggressive reaction
  • Convulsions
  • Drowsiness
  • Lack of energy or Fatigue
  • Skin rash, hives, or itching
  • Increased sweating
  • Behavioral or mood changes
  • Incontinence
  • Sudden loss of consciousness
  • Increase in body movements
  • Fever
  • Racing heartbeat
  • Dryness of the mouth
  • Inability to sit still

Incidence not known

  • Unusual tiredness or weakness
  • Talking or acting with excitement you cannot control
  • Severe mood or mental changes
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Pains in the stomach, side, or abdomen, possibly radiating to the back
  • Uncontrolled movements, especially of the face, neck, and back
  • Swelling of the face, ankles, or hands
  • Vomiting blood
  • Sore throat
  • Drooling
  • Blurred vision
  • Blindness
  • Abdominal pain
  • Bleeding gums
  • Haematuria (Blood in urine)
  • Depressed mood
  • Difficult in swallowing
  • Difficulty in breathing
  • Difficulty in speaking
  • Depressed vision
  • Bloody, black, or tarry stools
  • Chills
  • Darkened Urine
  • Chest pain and discomfort
  • Bloating
  • Lethargy
  • Irritability
  • Joint or muscle pain
  • Hostility
  • Feeling cold
  • High fever
  • Inflamed joints
  • Dry skin and hair
  • Eye pain
  • Hoarseness or husky voice
  • Feeling of discomfort
  • Weight gain
  • Unpleasant breath odor
  • Swollen or painful glands
  • Trouble breathing
  • Unusual behavior
  • Yellow eyes and skin
  • Unexplained bleeding or bruising
  • Twitching
  • Sores, ulcers, or white spots in the mouth or on the lips
  • Rash
  • Sweating
  • Indigestion
  • Stomach upset
  • Increased clotting time
  • Loss of appetite
  • Muscle twitching
  • Lower back or side pain
  • Lightheadedness
  • Muscle aches
  • Painful urination
  • Pale skin
  • Rapid weight gain
  • Shuffling walk
  • Right upper stomach pain and fullness
  • Red, irritated eyes

It is important to know that sertraline may elicit some side effects that may not warrant medical attention. With frequent dosing, your body may get used to the medicine and the side effects may start to resolve. It is the duty of your doctor to help you assuage these side effects, but make sure you play close attention to your body for any of these side effects.

More common side effects

  • Trouble sleeping
  • Sleepiness or unusual drowsiness
  • Heartburn
  • Diarrhea or loose stools
  • Belching
  • Acid or sour stomach
  • Decreased appetite or weight loss
  • Stomach or abdominal cramps, gas or pain

Less common

  • Increases appetite
  • Weight gain
  • Constipation
  • Cloudy urine
  • Stuffy or runny nose
  • Changes in vision
  • Agitation, anxiety, or nervousness
  • Burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • Bladder pain

Incidence not known

  • Unexplained weight loss
  • Severe sunburn
  • Unusual secretion of milk in woe=men
  • swelling of the breast in women
  • Increased urination
  • Flushed, dry skin
  • Increased hunger
  • Redness or other discoloration of the skin
  • Bladder pain
  • Frequent urge to urinate
  • Flushing or redness of the skin, with feeling of warmth or heat
  • Pain or tenderness around the eyes and cheekbones


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